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# Kidney stones (renal calculi)

11 May 2026

Kidney stones are hard, pebble-like deposits of minerals and salts — most commonly calcium oxalate — that form inside the kidneys when urine becomes too concentrated.

## Symptoms

Small stones may pass unnoticed. With bigger stones:

-   **Pain:** usually flank pain that starts suddenly and comes in waves. It often starts in the back or side, below the ribs, and radiates to the lower abdomen or groin.
-   **Urinary changes:** foul-smelling urine is more typical of an infection. For stones alone: cloudy urine, blood (pink, red or brown urine), urgency.

## Causes and risk factors

-   **Dehydration:** the number one risk you can change. The goal is more than 2.5 L of urine a day, which usually means about 2–3 L of water.
-   **Diet:** high sodium increases calcium in the urine. High animal protein raises uric acid and lowers citrate.
-   **Medicines:** topiramate and protease inhibitors can also cause stones.

## Kinds of stone

Stone

Key driver

Share of stones

Calcium oxalate

Low urine volume, high oxalate, low citrate

~80%

Calcium phosphate

Alkaline urine, hyperparathyroidism

~10%

Uric acid

Acidic urine, high-protein diet, gout

~5–10%

Struvite

Urinary infections with urease-producing bacteria

~5–10%

Cystine

Genetic cystinuria

~1%

## Prevention

-   **Citrate:** lemon or lime juice helps raise urinary citrate, which blocks stone formation.
-   **The calcium paradox:** calcium in the diet — rather than calcium supplements — binds oxalate in the gut and lowers the risk.
-   **Oxalates:** don’t cut out all oxalates unless you are known to excrete a lot of them. Pair high-oxalate foods with calcium-rich foods.

## Diagnosis and treatment

-   **CT scan:** a non-contrast CT is the gold standard for diagnosis.
-   **Alpha blockers:** tamsulosin can help stones of 5–10 mm pass, especially in the lower ureter.
-   **When to go to hospital:** fever with stone pain, vomiting that won’t stop, a single kidney with a blockage, or severe pain not controlled by medicines.

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